Professor Richard Eastell has been pivotal in numerous clinical trials, enhancing our knowledge of treatment efficacy and safety in osteoporosis. His extensive research and expertise have made him a key figure in osteoporosis care and treatment. In the upcoming lecture by Professor Richard Eastell, we will explore the transformative SABRE (Strategy to Advance BMD as a Regulatory Endpoint) project in osteoporosis. This initiative, a collaboration between the American Society for Bone and Mineral Research (ASBMR) and the Foundation for the National Institutes of Health (FNIH), aims to revolutionize osteoporosis drug development by establishing bone mineral density (BMD) as a surrogate endpoint for fractures in clinical trials. This approach promises to make trials more efficient, reduce costs, and accelerate the delivery of new treatments to patients. The lecture will cover the project's rationale, key scientific findings from extensive data analysis, regulatory milestones, and its potential impact on future osteoporosis treatment and broader medical research. Prof. Eastell's insights will illuminate the significant strides made in osteoporosis research, underscoring the importance of innovative approaches in medical science.

Following the advent of next-generation sequencing and single-cell sequencing, spatial transcriptomics and spatial multi-omics analyses have recently emerged and are becoming indispensable tools in biomedical research. However, bone tissue presents challenges for spatial transcriptomic analysis due to its requirement for lengthy fixation and decalcification, which poses a problem in maintaining RNA quality. Additionally, the competition among different platform technologies complicates the selection of the best solution for individual research objectives. My team was no exception, and we expended time, effort, and resources until we encountered Professor Thomas Andersen. Despite a sudden request via email, Dr. Andersen generously shared his research methods and expertise. Notably, at the ASBMR last October in Vancouver, during the 'Meet the Professor' session on bone tissue spatial transcriptomic analysis, the room was filled with eager attendees, reflecting the intense interest among bone researchers in this technology. We have invited him as the keynote speaker for this SSBH to facilitate more in-depth Q&A and face-to-face interactions.
Dr. Andersen is an Associate Professor at the University of Southern Denmark in Odense and holds an adjunct position at Aarhus University in Denmark. He has long been involved in research on bone tissue analysis and histomorphometry and has served as the president of the International Society of Bone Morphometry (ISBM). Dr. Andersen has also been active in the ASBMR, ECTS, and Bone Marrow Adipose Society (BMAS), where he has delivered numerous presentations. At our SSBH conference and workshop, Dr. Andersen will give two lectures, and we hope many members will attend to learn about the latest technological advances and their application in musculoskeletal research.